Zyban, Chantix and Depression
Friday, August 31st, 2007It’s been a couple of years now since the FDA approved Chantix (the generic is varenicline) as a smoking cessation aid, but many people still have questions about the medication.
Zyban (generic name, bupropion) has been used to help people kick the smoking habit since 1997. Under the name, Wellbutrin, the drug is also widely used to treat depression.
Dry mouth, increased sweating, headache, constipation, sleep problems, anxiety and fatigue are listed as the most common side effects. The general observation is that most people tolerate the medication fairly well. Zyban can, however, cause seizures in people with a history of seizures or eating disorders. And Zyban cannot be taken in combination with certain drugs.
Although Zyban is used for smoking cessation, it is an antidepressant and carries a warning from the FDA that some users may have suicidal thoughts when first taking the medication.
Chantix is not an antidepressant like Zyban. Chantix reduces your cravings for nicotine and, if you should smoke, that cigarette won’t be as pleasurable. In clinical trials, Chantix slightly outperforms Zyban.
Common side effects from Chantix are nausea, stomach discomfort, weakness, increased appetite, headache, weird dreams and insomnia. As with all medications, you should check with your doctor if you’re taking other drugs or supplements.
“Can Chantix cause depression?” is often asked. According to its manufacturer, depression and anxiety are frequent side effects.
Your doctor can help you select the medication most appropriate for you. Remember, too, that even when you’re using a cessation aid, the support of a program like the Trust’s Quit Smoking–Your Way! is crucial to successfully kicking the habit.



